解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:OBJECTIVES:To assess diagnoses and management of acute and chronic gout in primary care and rheumatology settings relative to 2006 European League Against Rheumatism (EULAR) gout recommendations. Secondary objectives were to describe patient demographics, clinical features, lifestyle modifications, and short- and mid-t...
journal_title:Joint bone spine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jbspin.2011.12.006
更新日期:2012-10-01 00:00:00
abstract::We report on a 46-year-old woman, who developed streptococcus B septic polyarthritis in the context of septicemia of urinary origin. This case revealed a Good's syndrome whose diagnosis was made on the basis of a profound hypogammaglobulinaemia, a large decrease of peripheral B cells and a thymoma disclosed on chest c...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2012.03.009
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To assess if the use of biological marker of bone resorption (CTX) feedback is a mean to improve persistence on monthly oral ibandronate. METHODS:One year prospective multicenter study using a cluster randomisation design with physicians as randomized units into two groups, A and B; in group B, physicians us...
journal_title:Joint bone spine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jbspin.2011.05.001
更新日期:2012-07-01 00:00:00
abstract::Retinoids are effective and widely prescribed in the treatment of severe acne. However their use can be associated with numerous side effects. Some rare cases of premature epiphyseal closure were reported. We present the case of a sixteen-year-old soccer player referred for progressive anterior pain in both knees, evo...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2011.11.001
更新日期:2012-05-01 00:00:00
abstract::Giant cell arteritis (GCA) affects middle-sized or large arteries in individuals over 50 years of age. GCA is characterized by a combination of focal inflammation responsible for arterial stenosis or occlusion and of systemic inflammation manifesting as polymyalgia rheumatica, a decline in general health, and inflamma...
journal_title:Joint bone spine
pub_type: 杂志文章,评审
doi:10.1016/j.jbspin.2011.09.015
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVES:Only a few studies have identified prognostic factors indicating risk of future knee arthroplasty in patients with osteoarthritis (OA) of the knee. The Osteoarthritis Initiative (OAI) is a National Institutes of Health and privately funded cohort study of 4796 persons with or at high risk of knee OA. The OAI...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2011.05.005
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVES:In the past decade many countries around the world have produced clinical practice guidelines to assist practitioners in providing a care that is aligned with the best evidence. The aim of this study was to present and compare the most established evidence-based recommendations for the management of chronic ...
journal_title:Joint bone spine
pub_type: 杂志文章,评审
doi:10.1016/j.jbspin.2011.03.019
更新日期:2012-03-01 00:00:00
abstract::Chronic recurrent multifocal osteomyelitis (CRMO), also known as chronic nonbacterial osteomyelitis, is an orphan disease that manifests as recurrent flares of inflammatory bone pain with or without a fever. The pain is related to one or more foci of nonbacterial osteomyelitis. To distinguish unifocal CRMO from a tumo...
journal_title:Joint bone spine
pub_type: 杂志文章,评审
doi:10.1016/j.jbspin.2011.02.010
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVES:Accumulating evidence suggests that gout is associated with increased overall and cardiovascular mortality. Using data from a large consecutive cohort of gout sufferers who were followed for 8 years, we investigated mortality among gout sufferers and compared the results with data from the general population...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2011.01.007
更新日期:2011-12-01 00:00:00
abstract::Cystic fibrosis (CF) is the most common autosomal recessive disease among Caucasians. It is due to a mutation in the cftr gene, which encodes the CF transmembrane conductance regulator (CFTR), a chloride channel located in the plasma membrane of mucus-secreting epithelial cells. Numerous other functions of the CFTR pr...
journal_title:Joint bone spine
pub_type: 杂志文章,评审
doi:10.1016/j.jbspin.2010.11.015
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:To determine in real-life conditions the safety of treatment with rituximab (RTX) in patients with rheumatoid arthritis (RA) regarding malignancies. METHODS:Analysis of safety data from a cohort of RA patients who received at least one course of RTX. RA patients with previous malignancies were followed-up an...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2010.11.012
更新日期:2011-10-01 00:00:00
abstract::We report the first case of an unusual sarcoidosic muscular involvement, complicated with radial nerve palsy. A 58-year-old woman suffering from a mediastinopulmonary sarcoidosis, was admitted for a driving deficit of the hands with a radially deviation during the wrist extension. She had been given a diagnosis of mot...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2011.03.007
更新日期:2011-10-01 00:00:00
abstract::Osteoarthritis (OA) is the most common human joint disorder. Its complex pathogenesis remains poorly understood but appears multifactorial. To date, no specific pharmacological agent has been identified to alter the disease course of OA. Calcification of articular cartilage is a hallmark of OA and evidence suggests it...
journal_title:Joint bone spine
pub_type: 杂志文章,评审
doi:10.1016/j.jbspin.2010.10.008
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:We examine the postural profile and muscular forces of the trunk and inferior members of patients with chronic low back pain. METHODS:In this study, we include 60 subjects forming two groups: a first group (G1) of 30 patients with chronic low back pain and a second group (G2) of 30 healthy subjects. Every su...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2010.09.008
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:Rheumatoid arthritis is associated with increased cardiovascular morbidity and mortality. We performed a systematic review of the literature and a meta-analysis to look for differences in the prevalence of traditional cardiovascular risk factor between RA patients and controls. METHODS:Medline database was s...
journal_title:Joint bone spine
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jbspin.2010.07.016
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To analyze the influence of anthropometry at birth on bone status and physical activity aptitudes of adult women. METHODS:Our population was composed of 70 women (17-29 years): 40 athletes and 30 controls. Athletes participated in various long-lasting and high-level weight-bearing sports (10.2 ± 2.2h ours/we...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2010.07.020
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVES:To study and compare the clinical and serological features of patients with elderly versus adult and younger onset of primary Sjögren's syndrome (pSS). METHODS:We analyzed retrospectively 336 consecutive pSS patients followed at our unit. They were subdivided into three groups according to the age at diseas...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2010.05.008
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:We assessed the efficacy, tolerance and cost of a 3 mg/kg starting dose of infliximab for ankylosing spondylitis (AS) and psoriatic arthritis (PsA). METHODS:We retrospectively followed-up 45 biologic-naive consecutive patients (11 with axial AS, 24 with axial and peripheral [mixed] AS and 10 with PsA) who we...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2010.04.017
更新日期:2011-01-01 00:00:00
abstract::Reported here is a 21-year-old female with isolated contracture of the rectus femoris muscle. Its possible relation to breech positioning, and the role of sonography for its diagnosis and close follow-up are discussed in the light of the relevant literature. ...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2010.07.013
更新日期:2011-01-01 00:00:00
abstract::Stickler syndrome is a group of rare genetic conditions (incidence, 1/7500 births) related to mutations in the collagen genes. Both the mutations and the clinical features vary widely across affected patients. The main manifestations are craniofacial birth defects, bone and joint symptoms, ocular abnormalities, and he...
journal_title:Joint bone spine
pub_type: 杂志文章,评审
doi:10.1016/j.jbspin.2010.03.012
更新日期:2011-01-01 00:00:00
abstract::Juvenile idiopathic arthritis (JIA) is a heterogeneous group of diseases, most of which differ from the main adult-onset inflammatory joint diseases. Nonsystemic forms of JIA (oligoarthritis, polyarthritis with or without rheumatoid factors, and spondyloarthropathies) are managed similarly to adult-onset rheumatoid ar...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2010.09.002
更新日期:2010-12-01 00:00:00
abstract::The management of postmenopausal osteoporosis has benefited from the recent introduction of several new drug classes and is now well standardized. However, none of the available osteoporosis drugs completely abolishes the occurrence of fractures. Therefore, criteria are needed to determine when the occurrence of a fra...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/S1297-319X(10)70008-7
更新日期:2010-12-01 00:00:00
abstract::Histone deacetylase inhibitors (HDIs) are a new class of compounds that are being developed for the treatment of malignancies such as cutaneous T-cell lymphoma. HDIs inhibit the removal of acetyl groups from histones. The histone acetylation process is dependent on two enzymes, histone acetyl transferase (HAT) and his...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2010.03.009
更新日期:2010-10-01 00:00:00
abstract::C-reactive protein (CRP) is an acute-phase protein whose concentration rises sharply during the inflammatory response (1000-fold). CRP belongs to the pentraxin family of proteins, of which a key property is the ability to opsonize apoptotic cells, which can then undergo phagocytosis without triggering an inflammatory ...
journal_title:Joint bone spine
pub_type: 杂志文章,评审
doi:10.1016/j.jbspin.2010.04.010
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Behcet's disease (BD) may complicate with arterial and venous thrombosis. The purpose of this work is to evaluate in an Italian group of BD patients with thrombotic events a large panel of inherited and acquired thrombophilic factors. METHODS:Thirty BD patients, of which nine with previously arterial or ven...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2010.02.022
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Infliximab (IFX) can be immunogenic for humans and lead to the formation of antibodies against IFX (anti-IFX Ab), which could induce acquired IFX resistance. OBJECTIVE:To test whether the presence of anti-IFX Ab and residual circulating IFX levels are associated with acquired IFX resistance in RA. METHODS:...
journal_title:Joint bone spine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jbspin.2010.02.021
更新日期:2010-07-01 00:00:00
abstract::Postmenopausal osteoporosis is characterized by bone remodeling alterations with an imbalance between excessive bone resorption and inadequate bone formation. At present, osteoporosis treatment rests on bone resorption inhibitors and, more specifically, on bisphosphonates. However, the introduction of anabolic agents ...
journal_title:Joint bone spine
pub_type: 杂志文章,评审
doi:10.1016/j.jbspin.2010.02.004
更新日期:2010-05-01 00:00:00
abstract::We describe a patient in whom sporadic Creutzfeldt-Jakob disease (sCJD) occurred one year after the onset of etanercept therapy for rheumatoid arthritis (RA). This association could be a chance occurrence. However, TNF-alpha has been implicated in the pathogenesis of neurodegeneration in sCJD and etanercept might wors...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2009.05.016
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Calcium pyrophosphate dihydrate crystal deposition disease (CPPD-CDD) has been associated to hypercalcemia. Familial hypocalciuric hypercalcemia (FHH) is a rare but important consideration in the differential diagnosis of hypercalcemia. This autosomal dominantly inherited condition is characterized by elevat...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2009.02.001
更新日期:2009-12-01 00:00:00
abstract::Rheumatology deals with many different entities among which dys/autoimmune diseases occupy a position of preponderance. This review focuses on the concept of complex genetic disease, which is illustrated by three different chronic inflammatory joint diseases: rheumatoid arthritis, systemic lupus erythematosus, and sys...
journal_title:Joint bone spine
pub_type: 杂志文章,评审
doi:10.1016/j.jbspin.2009.10.002
更新日期:2009-12-01 00:00:00
abstract::We report on an unusual case of a 40-year-old Caucasian male displaying severe Kawasaki-like symptoms. The disease lasted for seven years before diffuse coronary aneurysms occurred, leading to the patient's death, despite ongoing treatment by intravenous immunoglobulins (IVIGs). The patient had also been suffering fro...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2009.01.006
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To compare the frequency of different autoantibodies in a group of patients with Jaccoud's arthropathy (JA) secondary to systemic lupus erythematosus (SLE) with those without JA. METHODS:A group of SLE patients with JA was compared with another group of SLE patients without this complication, matched by age ...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2008.11.003
更新日期:2009-07-01 00:00:00
abstract::Evidence to guide assessment and management of patients with vasculitis is lacking for many important clinical questions. The evidence surrounding several common questions about management of vasculitis was reviewed. Patients with giant cell arteritis (GCA) are at risk for developing extra-cranial large vessel inflamm...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2009.05.005
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:To develop a diagnostic score for knee osteoarthritis flare-ups and to evaluate its sensitivity and specificity. METHODS:We used two epidemiological databases built using the same methodology. One database was from a general-practice study and served to develop the score, whereas the other was from a rheumat...
journal_title:Joint bone spine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jbspin.2008.07.018
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:To describe echographic abnormalities on the proximal (PIP) and distal (DIP) interphalangeal joints of healthy subjects. METHODS:Healthy asymptomatic volunteers under forty were enrolled. Ultrasonography was performed on PIP and DIP 2-5 in the presence of two operators. In B mode, synovial hypertophy and eff...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2008.06.017
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVES:This study was performed to investigate whether leptin mRNA expression is increased from peripheral blood mononuclear cells (PBMCs) of patients with active ankylosing spondylitis (AS) and whether it stimulates the production of pro-inflammatory cytokines. METHODS:Twenty patients with active AS were enrolled...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2008.04.018
更新日期:2009-03-01 00:00:00
abstract::We report the use of intra-articular Botulinum toxin A in two RA patients with persistently painful monoarthritis in ankle/feet joints. Both patients had monarticular pain despite a good response of all other joints to a combination therapy that included anti-tumor necrosis factor therapy. Both patients had failed int...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2008.05.006
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the diagnosing value of the Berlin algorithm, comparing to that of the established ESSG and Amor criteria in Chinese patients with undifferentiated spondyloarthropathy. METHODS:A total of 92 clinically diagnosed undifferentiated spondyloarthropathy patients with axial involvement were compared to...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2008.06.015
更新日期:2009-03-01 00:00:00
abstract::We present a case of multiple large juxta-articular painless masses involving both the elbows and right hip in a 27-year old south Asian male who presented with ulnar neuropathy and constitutional symptoms. Radiology, blood investigations and biopsy confirmed it to be hyperphosphatemic tumoral calcinosis. Patient was ...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2008.06.014
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVES:Candidate cell types for disc cell transplantation therapy include anulus fibrosus (AF) cells, chondrocytes, and bone marrow derived cells (BMDCs). We compared the disc matrix production in these three types of cells, before and after stimulation with rhBMP-2. There is no study extant that compares these thr...
journal_title:Joint bone spine
pub_type: 杂志文章
doi:10.1016/j.jbspin.2008.02.021
更新日期:2009-01-01 00:00:00